Selected Research Publications
Maria Echeveste Sanchez, ManHua Zhu, Sarah Magee, Shyenne Grady, Hayley Guerry, Tara N. Guhr-Lee, Charles R. Esther, Melissa A Herman, Electronic Vaporization of Nicotine Salt or Freebase produces differential effects on metabolism, neuronal activity and behavior in male and female C57BL/6J mice, Addiction Neuroscience, Volume 6, 2023, 100082, ISSN 2772-3925, https://doi.org/10.1016/j.addicn.2023.100082.
Effinger, D.P., Quadir, S.G., Ramage, M.C. et al. Sex-specific effects of psychedelic drug exposure on central amygdala reactivity and behavioral responding. Transl Psychiatry 13, 119 (2023). https://doi.org/10.1038/s41398-023-02414-5
Zhu, M., Rogers, N. G., Jahad, J. V., & Herman, M. A. (2023). Sex differences in the impact of electronic nicotine vapor on corticotropin-releasing factor receptor 1 neurons in the mouse ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience, JN-RM-2087-22. Advance online publication. https://doi.org/10.1523/JNEUROSCI.2087-22.2023
Echeveste Sanchez, M., Quadir, S. G., Whindleton, C. M., Hoffman, J. L., Faccidomo, S. P., Guhr Lee, T. N., Esther, C. R., Jr, Hodge, C. W., & Herman, M. A. (2022). The effects of electronic nicotine vapor on voluntary alcohol consumption in female and male C57BL/6 J mice. Drug and alcohol dependence, 241, 109676. https://doi.org/10.1016/j.drugalcdep.2022.109676
Weera, M. M., Agoglia, A. E., Douglass, E., Jiang, Z., Rajamanickam, S., Shackett, R. S., Herman, M. A., Justice, N. J., & Gilpin, N. W. (2022). Generation of a CRF1-Cre transgenic rat and the role of central amygdala CRF1 cells in nociception and anxiety-like behavior. eLife, 11, e67822. https://doi.org/10.7554/eLife.67822
Crofton, E. J., Zhu, M., Curtis, K. N., Nolan, G. W., O'Buckley, T. K., Morrow, A. L., & Herman, M. A. (2022). Medial prefrontal cortex-basolateral amygdala circuit dysfunction in chronic alcohol-exposed male rats. Neuropharmacology, 205, 108912. https://doi.org/10.1016/j.neuropharm.2021.108912
Quadir, S. G., Arleth, G. M., Jahad, J. V., Echeveste Sanchez, M., Effinger, D. P., & Herman, M. A. (2022). Sex differences in affective states and association with voluntary ethanol intake in Sprague-Dawley rats. Psychopharmacology, 239(2), 589–604. https://doi.org/10.1007/s00213-021-06052-x
Zhu M, Echeveste Sanchez M, Douglass EA, Jahad JV, Hanback TD, Guhr Lee TN, Esther CR Jr, Cole M, Roberts AJ, Herman MA. Electronic Nicotine Vapor Exposure Produces Differential Changes in Central Amygdala Neuronal Activity, Thermoregulation and Locomotor Behavior in Male Mice. eNeuro. 2021 Aug 11;8(4):ENEURO.0189-21.2021. doi: 10.1523/ENEURO.0189-21.2021. PMID: 34321216
Agoglia AE, Zhu M, Quadir SG, Bluitt MN, Douglass E, Hanback T, Tella J, Ying R, Hodge CW, Herman MA. Sex-specific plasticity in CRF regulation of inhibitory control in central amygdala CRF1 neurons after chronic voluntary alcohol drinking. Addict Biol. 2021 Jun 2:e13067. doi: 10.1111/adb.13067. Epub ahead of print.
Agoglia AE, Tella J, Herman MA. Sex differences in corticotropin releasing factor peptide regulation of inhibitory control and excitability in central amygdala corticotropin releasing factor receptor 1-neurons. Neuropharmacology. 2020 Dec 1;180:108296. doi: 10.1016/j.neuropharm.2020.108296. Epub 2020 Sep 17. PMID: 32950560
Agoglia AE, Zhu M, Ying R, Sidhu H, Natividad LA, Wolfe SA, Buczynski MW, Contet C, Parsons LH, Roberto M, Herman MA. Corticotropin-Releasing Factor Receptor-1 Neurons in the Lateral Amygdala Display Selective Sensitivity to Acute and Chronic Ethanol Exposure. eNeuro. 2020 Mar 5;7(2):ENEURO.0420-19.2020. doi: 10.1523/ENEURO.0420-19.2020. PMID: 32041742; PMCID:
Hughes B, Bohnsack J; O'Buckley T, Herman MA, Morrow AL. Chronic Ethanol Exposure and Withdrawal Impairs Synaptic GABAA Receptor-Mediated Neurotransmission in Deep Layer Prefrontal Cortex. Alcoholism: Clinical and Experimental Research. 2019 May;43(5):822-832.
Jimenez VA, Herman MA, Cuzon Carlson VC, Walter NA, Grant KA, Roberto M. Synaptic adaptations in the central amygdala and hypothalamic paraventricular nucleus associated with protracted ethanol abstinence in male rhesus monkeys. Neuropsychopharmacology. 2019 Apr;44(5):982-993.
Ghosh A, Coakley RC, Mascenik T, Rowell TR, Davis ES, Rogers K, Webster MJ, Dang H, Herring LE, Sassano MF, Livraghi-Butrico A, Van Buren SK, Graves LM, Herman MA, Randell SH, Alexis NE, Tarran R (2018). Chronic E-cigarette Exposure Alters the Human Bronchial Epithelial Proteome. Am J Respir Crit Care Med. Feb 2018. 198(1):67-76. PMID: 29481290.
Valentino RJ, Guyenet P, Hou XH, Herman M (2017). Central Network Dynamics Regulating Visceral and Humoral Functions. J Neurosci. Nov 2017. 37(45):10848-10854. PMID: 29118214
Borghese CM, Herman M, Snell LD, Lawrence KJ, Lee HY, Backos DS, Vanderlinden LA, Harris RA, Roberto M, Hoffman PL, Tabakoff B (2017). Novel Molecule Exhibiting Selective Affinity for GABAA Receptor Subtypes. Sci Rep. Jul 2017. 7(1):6230. PMID: 28740086.
Herman MA, Contet C, Roberto M (2016). A Functional Switch in Tonic GABA Currents Alters the Output of Central Amygdala Corticotropin Releasing Factor Receptor-1 Neurons Following Chronic Ethanol Exposure. Journal of Neuroscience. Oct 2016. 36(42):10729-10741. PMID: 27798128.
Buczynski MW, Herman MA, Hsu KL, Natividad LA, Irimia C, Polis IY, Pugh H, Chang JW, Niphakis MJ, Cravatt BF, Roberto M, Parsons LH (2016). Diacylglycerol lipase disinhibits VTA dopamine neurons during chronic nicotine exposure. Proc Natl Acad Sci U S A. Jan 2016. 113(4):1086-91. PMID: 26755579.
Grieder TE, Herman M, Contet C, Tan LA, Vargas-Perez H, Cohen A, Chwalek M, Maal-Bared G, Freiling J, Clarke L, Crawford E, Koebel P, Canonigo V, Sanna P, Roberto M, Kieffer BL, Sawchenko PE, Koob GF, van der Kooy D, George O (2014). CRF neurons in the ventral tegmental area control the aversive effects of nicotine withdrawal and promote escalation of nicotine intake. Nature Neuroscience. Dec 2014. (12): 1751–1758. PMID: 25402857.
Selected Reviews
Agoglia AE, Crofton EJ, Herman MA. Biological intersection of sex, age, and environment in the corticotropin releasing factor (CRF) system and alcohol. Neuropharmacology. 2020 Jun 15;170:108045. doi: 10.1016/j.neuropharm.2020.108045. Epub 2020 Mar 7. PMID: 32217364; PMCID: PMC7350391.
Agoglia AE, Herman MA (2018). The center of the emotional universe: Alcohol, stress, and CRF1 amygdala circuitry. Alcohol. Nov 2018. 72:61-63. PMID: 30220589.
Herman MA, Roberto M (2015). The Addicted Brain: understanding the neurophysiological mechanisms of addictive disorders. Front Integr Neurosci. Mar 2015. 19;9:18. PMID: 25852502.
Gilpin NW, Herman MA, Roberto M (2014). The Central Amygdala as an Integrative Hub for Anxiety and Alcohol Use Disorders. Biological Psychiatry. Sep 2014. PMID: 25433901.